Article
Influence of molecular subgroups on outcome of acute myeloid leukemia with normal karyotype in 141 patients undergoing salvage allogeneic stem cell transplantation in primary induction failure or beyond first relapse.
Haematologica - 1 Apr 2013
Pfeiffer Tim, Schleuning Michael, Mayer Jiri, Haude Karl-Heinz, Tischer Johanna, Buchholz Stefanie, Bunjes Donald, Bug Gesine, Holler Ernst, Meyer Ralf G, Greinix Hildegard, Scheid Christof, Christopeit Maximilian, Schnittger Susanne, Braess Jan, Schlimok Günter, Spiekermann Karsten, Ganser Arnold, Kolb Hans-Jochem, Schmid Christoph
Abstract excerpt
Based on molecular aberrations, in particular the NPM1 mutation (NPM1(mut)) and the FLT3 internal tandem duplication (Flt3-ITD), prognostic subgroups have been defined among patients with acute myeloid leukemia with normal karyotype. Whereas these subgroups are known to play an important role in...
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