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Article

Prognostic factors in normal karyotype acute myeloid leukemia in the absence of the FLT3-ITD mutation.

Leukemia research - 1 Apr 2011

Jiang Allan, Jiang Hua, Brandwein Joseph, Kamel-Reid Suzanne, Chang Hong

Abstract excerpt

Patients with normal karyotype acute myeloid leukemia (NK-AML) without the FLT3 internal tandem duplication (FLT3-ITD) mutation account for approximately 30% of all AML cases, and exhibit a heterogeneous clinical outcome. Except for NPM1 mutations, prognostic factors in this subgroup of AML are still unclear. Here we explored the impact of immunophenotypic markers along with NPM1 mutations and clinical features...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20684989
DOI: 10.1016/j.leukres.2010.07.021

Genes

EFS
NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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