Article
Genetic associations of the interleukin locus at 1q32.1 with clinical outcomes of cutaneous melanoma.
Journal of medical genetics - 1 Apr 2015
Rendleman Justin, Vogelsang Matjaz, Bapodra Anuj, Adaniel Christina, Silva Ines, Moogk Duane, Martinez Carlos N, Fleming Nathaniel, Shields Jerry, Shapiro Richard, Berman Russell, Pavlick Anna, Polsky David, Shao Yongzhao, Osman Iman, Krogsgaard Michelle, Kirchhoff Tomas
Abstract excerpt
BACKGROUND: Due to high melanoma immunogenicity, germline genetic variants in immune pathways have been studied for association with melanoma prognosis. However, limited candidate selection, inadequate power, or lack of independent validation have hampered the reproducibility of these prior findings, preventing personalised clinical applicability in melanoma prognostication. Our objective was to assess the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.