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Article

Conditional control of gene function by an invertible gene trap in zebrafish.

Proceedings of the National Academy of Sciences of the United States of America - 18 Sept 2012

Ni Terri T, Lu Jianjun, Zhu Meiying, Maddison Lisette A, Boyd Kelli L, Huskey Lindsey, Ju Bensheng, Hesselson Daniel, Zhong Tao P, Page-McCaw Patrick S, Stainier Didier Y, Chen Wenbiao

Abstract excerpt

Conditional mutations are essential for determining the stage- and tissue-specific functions of genes. Here we achieve conditional mutagenesis in zebrafish using FT1, a gene-trap cassette that can be stably inverted by both Cre and Flp recombinases. We demonstrate that intronic insertions in the...

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Identifiers

PMID: 22908272
DOI: 10.1073/pnas.1206131109
PMCID: PMC3458342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22908272-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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