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Article

Inference of selection based on temporal genetic differentiation in the study of highly polymorphic multigene families.

PloS one - 1 Jan 2012

McMullan Mark, van Oosterhout Cock

Abstract excerpt

The co-evolutionary arms race between host immune genes and parasite virulence genes is known as Red Queen dynamics. Temporal fluctuations in allele frequencies, or the 'turnover' of alleles at immune genes, are concordant with predictions of the Red Queen hypothesis. Such observations are often taken as evidence of host-parasite co-evolution. Here, we use computer simulations of the Major Histocompatibility...

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Identifiers

PMID: 22900006
DOI: 10.1371/journal.pone.0042119
PMCID: PMC3416836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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