Article
Cis-regulatory evolution in a wild primate: Infection-associated genetic variation drives differential expression of MHC-DQA1 in vitro.
Molecular ecology - 1 Sept 2017
Simons Noah D, Eick Geeta N, Ruiz-Lopez Maria J, Omeja Patrick A, Chapman Colin A, Goldberg Tony L, Ting Nelson, Sterner Kirstin N
Abstract excerpt
Few studies have combined genetic association analyses with functional characterization of infection-associated SNPs in natural populations of nonhuman primates. Here, we investigate the relationship between host genetic variation, parasitism and natural selection in a population of red colobus (Procolobus rufomitratus tephrosceles) in Kibale National Park, Uganda. We collected parasitological, cellular and...
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