Article
Parasite mediated homogenizing selection at the MHC in guppies.
Genetica - 1 Feb 2010
Fraser Bonnie A, Neff Bryan D
Abstract excerpt
Understanding the selective forces influencing genetic diversity is a fundamental goal of evolutionary ecology. The genes of the major histocompatibility complex (MHC) play a key role in the adaptive immune response of vertebrates and thus provide an excellent opportunity to examine the agents of selection on a functionally important gene. Here we examine the genetic architecture of the MHC class IIB genes in 10...
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