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Article

Sexual selection and the evolutionary dynamics of the major histocompatibility complex.

Proceedings. Biological sciences - 7 Dec 2014

Jan Ejsmond Maciej, Radwan Jacek, Wilson Anthony B

Abstract excerpt

The genes of the major histocompatibility complex (MHC) are a key component of the adaptive immune system and among the most variable loci in the vertebrate genome. Pathogen-mediated natural selection and MHC-based disassortative mating are both thought to structure MHC polymorphism, but their effects have proven difficult to discriminate in natural systems. Using the first model of MHC dynamics incorporating...

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Identifiers

PMID: 25339723
DOI: 10.1098/rspb.2014.1662
PMCID: PMC4213641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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