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Article

Depletion of MHC supertype during domestication can compromise immunocompetence.

Molecular ecology - 1 Feb 2021

Smallbone Willow, Ellison Amy, Poulton Simon, van Oosterhout Cock, Cable Joanne

Abstract excerpt

The major histocompatibility complex (MHC) plays an important role in infectious disease resistance. The presence of certain MHC alleles and functionally similar groups of MHC alleles (i.e., supertypes) has been associated with resistance to particular parasite species. Farmed and domesticated fish stocks are often depleted in their MHC alleles and supertype diversity, possibly as a consequence of artificial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33274493
DOI: 10.1111/mec.15763
PMCID: PMC7898906

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