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Article

Differentiated umbilical cord matrix stem cells as a new in vitro model to study early events during hepatitis B virus infection

17 Aug 2012

Abstract excerpt

UNLABELLED: The role of cell differentiation state on hepatitis B virus (HBV) replication has been well demonstrated, whereas how it determines cell susceptibility to HBV entry is far less understood. We previously showed that umbilical cord matrix stem cells (UCMSC) can be differentiated towards hepatocyte-like cells in vitro. In this study we infected undifferentiated (UD-) and differentiated (D-) UCMSCs with...

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PMID: 22898823
DOI: 10.1002/hep.26006

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