Article
Differentiation of human umbilical cord mesenchymal stromal cells into low immunogenic hepatocyte-like cells.
Cytotherapy - 1 Jan 2009
Zhao Qinjun, Ren Hongying, Li Xiyuan, Chen Zhong, Zhang Xiangyu, Gong Wei, Liu Yongjun, Pang Tianxiang, Han Zhong Chao
Abstract excerpt
BACKGROUND AIMS: Mesenchymal stromal cells (MSC) isolated from several human tissues have been known to differentiate into the hepatic lineage in vitro, but the immunogenicity of the differentiated hepatocyte-like cells (DHC) has not been reported. Umbilical cord (UC) MSC are thought to be an attractive cell source for cell therapy because of their young age and low infection rate compared with adult tissue MSC....
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