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Article

Human pluripotent stem cell-derived hepatocyte-like cells for hepatitis D virus studies

2023-10-13

Abstract excerpt

Current culture systems available for studying hepatitis D virus (HDV) are suboptimal. In this study, we demonstrate that hepatocyte-like cells (HLCs) derived from human pluripotent stem cells (hPSCs) are fully permissive to HDV infection across various tested genotypes. When co- infected with the helper hepatitis B virus (HBV) or transduced to express the HBV envelope protein HBsAg, HLCs effectively secrete infec...

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Literature Corpus work
dcb5b9b8-e718-5bd4-8aaa-11ca9dea62a9
DOI
10.1101/2023.10.13.561984
Open publication

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Human pluripotent stem cell-derived hepatocyte-like cells for hepatitis D virus studiesDOI 10.1101/2023.10.13.561984
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