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Advances and Challenges in Studying Hepatitis B Virus In Vitro

14 Jan 2016

Abstract excerpt

Hepatitis B virus (HBV) is a small DNA virus that infects the liver. Current anti-HBV drugs efficiently suppress viral replication but do not eradicate the virus due to the persistence of its episomal DNA. Efforts to develop reliable in vitro systems to model HBV infection, an imperative tool for studying HBV biology and its interactions with the host, have been hampered by major limitations at the level of the...

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PMID: 26784218
DOI: 10.3390/v8010021

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