A common variant in the precursor miR-146a sequence does not predispose to cholangiocarcinoma in a large European cohort.

doi:10.1016/s1499-3872(12)60200-8

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A common variant in the precursor miR-146a sequence does not predispose to cholangiocarcinoma in a large European cohort.

Hepatobiliary & pancreatic diseases international : HBPD INT - 15 Aug 2012

Mihalache Florentina, Hoblinger Aksana, Acalovschi Monica, Sauerbruch Tilman, Lammert Frank, Zimmer Vincent

Abstract excerpt

BACKGROUND: Micro-RNAs (miRNAs) are small, non-coding RNA species considered to fine-tune basic cellular functions by modulating target gene translation and/or mRNA stability. A common G/C polymorphism (rs2910164) in the precursor (pre-) miR-146a gene engaged in NF-κB signaling and apoptosis path...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Academic Medical Centers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bile Duct Neoplasms

Share to Bile Ducts, Intrahepatic

Share to Chi-Square Distribution

Share to Cholangiocarcinoma

Share to Germany

Share to RNA Precursors

Share to Romania

Source

Open in PubMed

Identifiers

PMID: 22893469
DOI: 10.1016/s1499-3872(12)60200-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22893469-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A common variant in the precursor miR-146a sequence does not predispose to cholangiocarcinoma in a large European cohort.PMID 22893469Read ↗

No association of pre-microRNA-146a rs2910164 polymorphism and risk of hepatocellular carcinoma development in Turkish population: a case-control study.Semantic proximity Read ↗

A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma.Semantic proximity Read ↗

A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma.Semantic proximity Read ↗

Association between miR-146a rs2910164 polymorphism and specific cancer susceptibility: an updated meta-analysis.Semantic proximity Read ↗

A functional polymorphism in Pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population.Semantic proximity Read ↗

A single nucleotide polymorphism in microRNA-146a is associated with the risk for nasopharyngeal carcinoma.Semantic proximity Read ↗

Association of single nucleotide polymorphism miRNA-146a (rs2910164) with increased predisposition to oral squamous cell carcinoma in central India population.Semantic proximity Read ↗

Meta-analysis confirms that a common G/C variant in the pre-miR-146a gene contributes to cancer susceptibility and that ethnicity, gender and smoking status are risk factors.Semantic proximity Read ↗

A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo.Semantic proximity Read ↗

The association of common functional polymorphisms in mir-146a and mir-196a2 and hepatocellular carcinoma risk: evidence from a meta-analysis.Semantic proximity Read ↗

A genetic variant in miR-146a modifies colorectal cancer susceptibility in a Chinese population.Semantic proximity Read ↗

Polymorphic mature microRNAs from passenger strand of pre-miR-146a contribute to thyroid cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.