A functional polymorphism in Pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population.

doi:10.1089/dna.2011.1596

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A functional polymorphism in Pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population.

DNA and cell biology - 1 Jul 2012

Zhou Fengying, Zhu Haixia, Luo Dewei, Wang Meilin, Dong Xiao, Hong Yan, Lu Bo, Zhou Yan, Zhou Jianwei, Zhang Zhengdong, Gong Weida

Abstract excerpt

MicroRNAs play an important role in regulating gene expression at the post-transcriptional level and are involved in numerous physiological processes. Aberrant expression of MicroRNAs is considered to participate in occurrence and progression of human cancers. A G>C polymorphism, rs2910164, which is located in the sequence of miR-146a precursor, could alter mature miR-146a expression and has been suggested to...

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PMID: 22455393
DOI: 10.1089/dna.2011.1596

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