Article
A functional polymorphism in the pre-miR-146a gene is associated with risk and prognosis in adult glioma.
Journal of neuro-oncology - 1 Dec 2011
Permuth-Wey Jennifer, Thompson Reid C, Burton Nabors L, Olson Jeffrey J, Browning James E, Madden Melissa H, Ann Chen Y, Egan Kathleen M
Abstract excerpt
MicroRNAs (miRNAs) are non-coding RNAs that function as post-transcriptional regulators of tumor suppressors and oncogenes. Single nucleotide polymorphisms (SNPs) in miRNAs may contribute to carcinogenesis by altering expression of miRNAs and their targets. A G>C polymorphism (rs2910164) in the m...
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