A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma.

doi:10.1093/carcin/bgn195

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma.

Carcinogenesis - 1 Nov 2008

Xu Teng, Zhu Ying, Wei Qing-Kun, Yuan Yunfei, Zhou Fan, Ge Yi-Yuan, Yang Jian-Rong, Su Hang, Zhuang Shi-Mei

Abstract excerpt

A G > C polymorphism (rs2910164) is located in the stem region opposite to the mature miR-146a sequence, which results in a change from G:U pair to C:U mismatch in the stem structure of miR-146a precursor. Here, we elucidated the biological significance of this polymorphism, based on cancer association study and cell model system. The cancer association study included 479 hepatocellular carcinoma (HCC) and 504...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blotting, Northern

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Hepatocellular

Share to Case-Control Studies

Share to DNA Primers

Share to Liver Neoplasms

Share to MicroRNAs

Share to NIH 3T3 Cells

Share to Risk Factors

Source

Open in PubMed

Identifiers

PMID: 18711148
DOI: 10.1093/carcin/bgn195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma.PMID 18711148Read ↗

A genetic variant in miR-146a modifies colorectal cancer susceptibility in a Chinese population.Semantic proximity Read ↗

Association of the microRNA-499 variants with susceptibility to hepatocellular carcinoma in a Chinese population.Semantic proximity Read ↗

A functional polymorphism in Pre-miR-146a is associated with susceptibility to gastric cancer in a Chinese population.Semantic proximity Read ↗

miR-146a rs2910164 and hepatocellular carcinoma: a meta-analysis.Semantic proximity Read ↗

The association of common functional polymorphisms in mir-146a and mir-196a2 and hepatocellular carcinoma risk: evidence from a meta-analysis.Semantic proximity Read ↗

No association of pre-microRNA-146a rs2910164 polymorphism and risk of hepatocellular carcinoma development in Turkish population: a case-control study.Semantic proximity Read ↗

A functional varient in microRNA-146a is associated with risk of esophageal squamous cell carcinoma in Chinese Han.Semantic proximity Read ↗

miR-146a G>C polymorphisms and risk of hepatocellular carcinoma in a Chinese population.Semantic proximity Read ↗

Contributions of polymorphisms in miR146a, miR196a, and miR499 to the development of hepatocellular carcinoma.Semantic proximity Read ↗

A functional polymorphism in Pre-miR-146a gene is associated with prostate cancer risk and mature miR-146a expression in vivo.Semantic proximity Read ↗

Three common functional polymorphisms in microRNA encoding genes in the susceptibility to hepatocellular carcinoma: a systematic review and meta-analysis.Semantic proximity Read ↗

Association of a single-nucleotide polymorphism within the miR-146a gene with susceptibility for acute-on-chronic hepatitis B liver failure.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.