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Article

Crystal structures of the Cid1 poly (U) polymerase reveal the mechanism for UTP selectivity.

Nucleic acids research - 1 Oct 2012

Lunde Bradley M, Magler Iris, Meinhart Anton

Abstract excerpt

Polyuridylation is emerging as a ubiquitous post-translational modification with important roles in multiple aspects of RNA metabolism. These poly (U) tails are added by poly (U) polymerases with homology to poly (A) polymerases; nevertheless, the selection for UTP over ATP remains enigmatic. We report the structures of poly (U) polymerase Cid1 from Schizoscaccharomyces pombe alone and in complex with UTP, CTP,...

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Identifiers

PMID: 22885303
DOI: 10.1093/nar/gks740
PMCID: PMC3479196

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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