Article
Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype.
Free radical biology & medicine - 15 Sept 2012
Ramamoorthy Mahesh, Sykora Peter, Scheibye-Knudsen Morten, Dunn Christopher, Kasmer Cindy, Zhang Yongqing, Becker Kevin G, Croteau Deborah L, Bohr Vilhelm A
Abstract excerpt
Alzheimer disease (AD) is a major health problem in the United States, affecting one in eight Americans over the age of 65. The number of elderly suffering from AD is expected to continue to increase over the next decade, as the average age of the U.S. population increases. The risk factors for and etiology of AD are not well understood; however, recent studies suggest that exposure to oxidative stress may be a...
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