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Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses

9 Feb 2004

Abstract excerpt

The pathogenesis of incipient Alzheimer's disease (AD) has been resistant to analysis because of the complexity of AD and the overlap of its early-stage markers with normal aging. Gene microarrays provide new tools for addressing complexity because they allow overviews of the simultaneous activity of multiple cellular pathways. However, microarray data interpretation is often hindered by low statistical power,...

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PMID: 14769913
DOI: 10.1073/pnas.0308512100

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