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Molecular Mechanisms and Genetics of Oxidative Stress in Alzheimer’s Disease

13 Nov 2019

Abstract excerpt

Alzheimer's disease is the most common neurodegenerative disorder that can cause dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress which interconnects with other processes such as amyloid-β deposition, tau hyperphosphorylation, and tangle formation. This review discusses current thoughts on molecular mechanisms that may relate oxidative stress to Alzheimer's disease and...

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PMID: 31744008
DOI: 10.3233/jad-190863

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