Article
Genotoxicity in Alzheimer's disease: role of amyloid.
Current Alzheimer research - 1 Sept 2006
Suram Anitha, Venugopal Chitra, Prakasam Annamalai, Sambamurti Kumar
Abstract excerpt
Alzheimer's disease (AD) is a complex neurodegenerative disorder pathologically identified by the presence of extracellular senile plaques (SP) with a proteinaceous core composed of aggregates of the amyloid peptide (Abeta) and intracellular aggregates of the microtubule-associated protein tau (tau) as neurofibrillary tangles (NFTs). These hallmarks consist of abnormally folded proteinaceous components that are...
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