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Article

Role of primary aging hallmarks in Alzheimer´s disease

29 Nov 2022

Abstract excerpt

Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely threatens the health of the elderly and causes significant economic and social burdens. The causes of AD are complex and include heritable but mostly aging-related factors. The primary aging hallmarks include genomic instability, telomere wear, epigenetic changes, and loss of protein stability, which play a dominant role in the...

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PMID: 36593969
DOI: 10.7150/thno.79535

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