Article
Characterization of pncA mutations of pyrazinamide-resistant Mycobacterium tuberculosis in Turkey.
The new microbiologica - 1 Apr 2009
Yüksel Pelin, Tansel Ozlem
Abstract excerpt
Mutations in the pyrazinamidase (PZase) gene (pncA) are considered the major mechanism of pyrazinamide (PZA) resistance in Mycobacterium tuberculosis. The aim of this study was designed to determine pncA mutations among ten PZA resistant and two PZA susceptible M. tuberculosis strains from Turkey and also to compare the PZase activity of them with the genotype. All isolates were identified by BACTEC NAP...
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