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Article

Interaction of the DRD3 and BDNF gene variants in subtyped bipolar disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 3 Dec 2012

Lee Sheng-Yu, Chen Shiou-Lan, Chen Shih-Heng, Chu Chun-Hsien, Chang Yun-Hsuan, Lin Shih-Hsien, Huang San-Yuan, Tzeng Nian-Sheng, Kuo Po-Hsiu, Lee I Hui, Yeh Tzung Lieh, Yang Yen Kuang, Lu Ru-Band

Abstract excerpt

OBJECTIVES: Bipolar disorder is a severe mental disorder with prominent genetic etiologic factors. Dopaminergic dysfunction has been implicated in the pathogenesis of bipolar disorder, which suggests that the dopamine D3 receptor gene (DRD3) is a strong candidate gene. The brain-derived neurotrophic factor (BDNF) gene has been implicated in the etiology of bipolar disorder. We examined the association between the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

Identifiers

PMID: 22877924
DOI: 10.1016/j.pnpbp.2012.07.015

Genes

BDNF
DRD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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