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Article

The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.

American journal of human genetics - 1 Sept 2002

Neves-Pereira Maria, Mundo Emanuela, Muglia Pierandrea, King Nicole, Macciardi Fabio, Kennedy James L

Abstract excerpt

Bipolar disorder (BP) is a severe psychiatric disease, with a strong genetic component, that affects 1% of the population worldwide and is characterized by recurrent episodes of mania and depression. Brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis of mood disorders, and the aim of the present study was to test for the presence of linkage disequilibrium between two polymorphisms in...

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Identifiers

PMID: 12161822
DOI: 10.1086/342288
PMCID: PMC379201

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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