Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders.

doi:10.3109/15622975.2014.953011

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Article

Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Apr 2015

Zai Clement C, Manchia Mirko, Sønderby Ida Elken, Yilmaz Zeynep, De Luca Vincenzo, Tiwari Arun K, Squassina Alessio, Zai Gwyneth C, Shaikh Sajid A, Strauss John, King Nicole, Le Foll Bernard, Kaplan Allan S, Finseth Per I, Vaaler Arne E, Djurovic Srdjan, Andreassen Ole A, Vincent John B, Kennedy James L

Abstract excerpt

OBJECTIVES: Suicide is a serious public health concern, and it is partly genetic. The brain-derived neurotrophic factor (BDNF) gene has been a strong candidate in genetic studies of suicide (Dwivedi et al., Arch Gen Psychiatry 2010;60:804-815; Zai et al., Prog Neuropsychopharmacol Biol Psychiatry 2012;34:1412-1418) and BDNF regulates the expression of the dopamine D3 receptor. OBJECTIVE: We examined the role of...

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Identifiers

PMID: 25264289
DOI: 10.3109/15622975.2014.953011
PMCID: PMC4377309

Genes

BDNF
DRD3

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