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Article

Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism.

Novartis Foundation symposium - 1 Jan 2008

Fan Jinbo, Sklar Pamela

Abstract excerpt

Bipolar disorder is a chronic severe mood disorder that has been consistently demonstrated to have a strong inherited component. Traditional approaches to gene discovery have produced conflicting results regarding the association between genes and bipolar disorder. Numerous genes have been proposed as associated with bipolar disorder. This paper will focus on one of these, brain-derived neurotrophic factor...

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Source

Identifiers

PMID: 18497095
DOI: 10.1002/9780470751251.ch5

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Genetics of bipolar disorder: focus on BDNF Val66Met polymorphism.PMID 18497095Read ↗

Association between brain-derived neurotrophic factor genetic polymorphism Val66Met and susceptibility to bipolar disorder: a meta-analysis.Semantic proximity Read ↗

The role of brain-derived neurotrophic factor (BDNF) Val66Met genetic polymorphism in bipolar disorder: a case-control study, comorbidities, and meta-analysis of 16,786 subjects.Semantic proximity Read ↗

Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene.Semantic proximity Read ↗

Meta-analysis reveals no association of the Val66Met polymorphism of brain-derived neurotrophic factor with either schizophrenia or bipolar disorder.Semantic proximity Read ↗

Role of BDNF in bipolar and unipolar disorder: clinical and theoretical implications.Semantic proximity Read ↗

BDNF Val66Met polymorphism and bipolar disorder in European populations: A risk association in case-control, family-based and GWAS studies.Semantic proximity Read ↗

The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.Semantic proximity Read ↗

Brain derived neurotrophic factor (BDNF) Val66Met polymorphism is not risk factor for bipolar disorderSemantic proximity Read ↗

No association between the Val66Met polymorphism of the brain-derived neurotrophic factor gene and bipolar disorder in a Japanese population: a multicenter study.Semantic proximity Read ↗

Brain-derived neurotrophic factor as a potential risk locus for bipolar disorder: evidence, limitations, and implications.Semantic proximity Read ↗

The BDNF Val66Met polymorphism and plasma brain-derived neurotrophic factor levels in Han Chinese patients with bipolar disorder and schizophrenia.Semantic proximity Read ↗

Genetic variation of brain-derived neurotrophic factor (BDNF) in bipolar disorder: case-control study of over 3000 individuals from the UK.Semantic proximity Read ↗

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