Article
The role of BDNF genetic polymorphisms in bipolar disorder with psychiatric comorbidities.
Journal of affective disorders - 1 Jun 2011
Neves Fernando Silva, Malloy-Diniz Leandro, Romano-Silva Marco Aurélio, Campos Simone Becho, Miranda Débora Marques, De Marco Luiz, Figueira Patrícia Gomes, Krebs Marie-Odile, Correa Humberto
Abstract excerpt
BACKGROUND: Bipolar disorder (BD) is a complex disorder where genetic factors play a major role in its etiology. Probably, no other axis I diagnosis has a co-morbidity prevalence as high as BD. Since BDNF is involved in different ways in various psychiatric disorders we hypothesized that its genetic polymorphisms could be associated with the co-morbidity phenomenon in BD. METHODS: We studied 320 subjects (160 BD...
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