Article
Rabconnectin3α promotes stable activity of the H+ pump on synaptic vesicles in hair cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Aug 2012
Einhorn Zev, Trapani Josef G, Liu Qianyong, Nicolson Teresa
Abstract excerpt
Acidification of synaptic vesicles relies on the vacuolar-type ATPase (V-ATPase) and provides the electrochemical driving force for neurotransmitter exchange. The regulatory mechanisms that ensure assembly of the V-ATPase holoenzyme on synaptic vesicles are unknown. Rabconnectin3α (Rbc3α) is a potential candidate for regulation of V-ATPase activity because of its association with synaptic vesicles and its...
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