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Article

Synaptojanin1 is required for temporal fidelity of synaptic transmission in hair cells.

PLoS genetics - 1 May 2009

Trapani Josef G, Obholzer Nikolaus, Mo Weike, Brockerhoff Susan E, Nicolson Teresa

Abstract excerpt

To faithfully encode mechanosensory information, auditory/vestibular hair cells utilize graded synaptic vesicle (SV) release at specialized ribbon synapses. The molecular basis of SV release and consequent recycling of membrane in hair cells has not been fully explored. Here, we report that comet, a gene identified in an ENU mutagenesis screen for zebrafish larvae with vestibular defects, encodes the lipid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19424431
DOI: 10.1371/journal.pgen.1000480
PMCID: PMC2673039

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Synaptojanin1 is required for temporal fidelity of synaptic transmission in hair cells.PMID 19424431Read ↗

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L-type voltage-gated calcium channel agonists improve hearing loss and modify ribbon synapse morphology in the zebrafish model of Usher Syndrome Type 1Semantic proximity Read ↗

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