Article
Otoferlin: a multi-C2 domain protein essential for hearing.
Trends in neurosciences - 1 Nov 2012
Pangršič Tina, Reisinger Ellen, Moser Tobias
Abstract excerpt
Sound is encoded at synapses between cochlear inner hair cells and the auditory nerve. These synapses are anatomically and functionally specialized to transmit acoustic information with high fidelity over a lifetime. The molecular mechanisms of hair-cell transmitter release have recently attracted substantial interest. Here we review progress toward understanding otoferlin, a multi-C2 domain protein identified a...
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