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Article

Deep Panning: Steps towards Probing the IgOme

1 Aug 2012

Abstract excerpt

BACKGROUND: Polyclonal serum consists of vast collections of antibodies, products of differentiated B-cells. The spectrum of antibody specificities is dynamic and varies with age, physiology, and exposure to pathological insults. The complete repertoire of antibody specificities in blood, the IgOme, is therefore an extraordinarily rich source of information-a molecular record of previous encounters as well as a...

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PMID: 22870226
DOI: 10.1371/journal.pone.0041469

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