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Deconvoluting virome-wide antibody epitope reactivity profiles

15 Dec 2021

Abstract excerpt

BACKGROUND: Comprehensive characterization of exposures and immune responses to viral infections is critical to a basic understanding of human health and disease. We previously developed the VirScan system, a programmable phage-display technology for profiling antibody binding to a library of peptides designed to span the human virome. Previous VirScan analytical approaches did not carefully account for antibody...

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PMID: 34922324
DOI: 10.1016/j.ebiom.2021.103747

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