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Article

On the roles and regulation of chondroitin sulfate and heparan sulfate in zebrafish pharyngeal cartilage morphogenesis.

The Journal of biological chemistry - 28 Sept 2012

Holmborn Katarina, Habicher Judith, Kasza Zsolt, Eriksson Anna S, Filipek-Gorniok Beata, Gopal Sandeep, Couchman John R, Ahlberg Per E, Wiweger Malgorzata, Spillmann Dorothe, Kreuger Johan, Ledin Johan

Abstract excerpt

The present study addresses the roles of heparan sulfate (HS) proteoglycans and chondroitin sulfate (CS) proteoglycans in the development of zebrafish pharyngeal cartilage structures. uxs1 and b3gat3 mutants, predicted to have impaired biosynthesis of both HS and CS because of defective formation of the common proteoglycan linkage tetrasaccharide were analyzed along with ext2 and extl3 mutants, predicted to have...

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Identifiers

PMID: 22869369
DOI: 10.1074/jbc.M112.401646
PMCID: PMC3460485

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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