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Article

Similar predictions of etravirine sensitivity regardless of genotypic testing method used: comparison of available scoring systems.

Antiviral therapy - 1 Jan 2012

Vingerhoets Johan, Nijs Steven, Tambuyzer Lotke, Hoogstoel Annemie, Anderson David, Picchio Gaston

Abstract excerpt

BACKGROUND: The aims of this study were to compare various genotypic scoring systems commonly used to predict virological outcome to etravirine, and examine their concordance with etravirine phenotypic susceptibility. METHODS: Six etravirine genotypic scoring systems were assessed: Tibotec 2010 (based on 20 mutations; TBT 20), Monogram, Stanford HIVdb, ANRS, Rega (based on 37, 30, 27 and 49 mutations,...

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PMID: 22869341
DOI: 10.3851/IMP2275

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