Article
Accuracy, precision, and consistency of expert HIV type 1 genotype interpretation: an international comparison (The GUESS Study).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Jul 2005
Zolopa Andrew R, Lazzeroni Laura C, Rinehart Alex, Vezinet Françoise Brun, Clavel François, Collier Ann, Conway Brian, Gulick Roy M, Holodniy Mark, Perno Carlo-Frederico, Shafer Robert W, Richman Douglas D, Wainberg Mark A, Kuritzkes Daniel R
Abstract excerpt
BACKGROUND: Resistance testing is considered standard of care in HIV medicine, but there is no standard interpretation system for genotype tests. We sought to determine how much agreement exists within a group of experts in the interpretation of complex genotypes. METHODS: Genotypes from clinical specimens were sent to an international panel of 12 resistance experts. Phenotypic susceptibility testing of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.