Article
A comparison of HIV-1 drug susceptibility as provided by conventional phenotyping and by a phenotype prediction tool based on viral genotype.
Journal of medical virology - 1 Oct 2009
Van Houtte Margriet, Picchio Gaston, Van Der Borght Koen, Pattery Theresa, Lecocq Pierre, Bacheler Lee T
Abstract excerpt
Concordance between the conventional HIV-1 phenotypic drug resistance assay, PhenoSense (PS), and vircoTYPE HIV-1 (vT), a drug resistance assay based on prediction of the phenotype, was investigated in a data set from the Stanford HIV Resistance database (hivdb). Depending on the drug, between 287 and 902 genotype-phenotype data pairs were available for comparisons. Test results (fold-change values) in the two...
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