A polymorphism at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the risk of epithelial ovarian cancer.

doi:10.1016/j.cancergen.2012.04.010

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Article

A polymorphism at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the risk of epithelial ovarian cancer.

Cancer genetics - 1 Jan 2000

Wang Cuiju, Guo Zhanjun, Wu Chensi, Li Yan, Kang Shan

Abstract excerpt

MicroRNAs (miRNAs) bind to the 3' untranslated regions (UTRs) of messenger RNAs, where they interfere with the translation of genes that regulate cell differentiation, apoptosis, and tumorigenesis. SET8 reportedly methylates TP53 and regulates genomic stability. We analyzed a single nucleotide polymorphism (rs16917496) within the miR-502 mRNA seed region of the 3' UTR of SET8 in Chinese epithelial ovarian cancer...

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PMID: 22867998
DOI: 10.1016/j.cancergen.2012.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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A polymorphism at the miR-502 binding site in the 3' untranslated region of the SET8 gene is associated with the risk of epithelial ovarian cancer.PMID 22867998Read ↗

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