Article
A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer.
Oncotarget - 7 Jun 2016
Liu Ben, Zhang Xining, Song Fengju, Liu Qun, Dai Hongji, Zheng Hong, Cui Ping, Zhang Lina, Zhang Wei, Chen Kexin
Abstract excerpt
A single-nucleotide polymorphism (SNP) locus rs16917496 (T > C) within the 3'-untranslated region (3'-UTR) of SET8 was associated with susceptibility in several malignancies including breast cancer. To further elucidate the prognostic relevance of this SNP in breast cancer, we conducted a clinical study as well as SET8 expression analysis in a cohort of 1,190 breast cancer patients. We demonstrated the expression...
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