Article
Prognostic value of microRNA 502 binding site SNP in the 3'-untranslated region of the SET8 gene in patients with non-Hodgkin's lymphoma.
Tumori - 1 Jan 2000
Diao Lanping, Su Huiling, Wei Guangchuan, Li Tao, Gao Yuhuan, Zhao Guimin, Guo Zhanjun
Abstract excerpt
AIMS AND BACKGROUND: A number of important cancer-associated covalent modifications of histone genes can be regulated by microRNAs (miRNAs) that bind to their target sites in the 3'-untranslated regions. We evaluated the effect of single-nucleotide polymorphisms (SNPs) at the miR-502 binding site in the 3'-untranslated region of the SET8 gene on the clinical outcome of non-Hodgkin's lymphomas (NHL). METHODS AND...
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