Article
Bipolar disorder, brain-derived neurotrophic factor (BDNF) Val66Met polymorphism and brain morphology.
PloS one - 1 Jan 2012
Teh Cheryl Ann, Lee Tih-Shih, Kuchibhatla Margaratha, Ashley-Koch Allison, Macfall James, Krishnan Ranga, Beyer John
Abstract excerpt
In this study of the effect of bipolar status and presence of BDNF Val66Met polymorphism on differences in regional brain volumes, we hypothesized based on previous studies that 1) bipolar subjects will have smaller regional brain volumes than healthy controls; 2) BDNF Met66 allele carriers within the same population are likely to have smaller regional brain volumes as compared to Val66 homozygyotes. In our...
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