Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses.

PloS one - 1 Jan 2012

Popova Lyubov, Smith Kenneth, West Ann H, Wilson Patrick C, James Judith A, Thompson Linda F, Air Gillian M

Abstract excerpt

H3N2 influenza viruses have now circulated in the human population for 43 years since the pandemic of 1968, accumulating sequence changes in the hemagglutinin (HA) and neuraminidase (NA) that are believed to be predominantly due to selection for escape from antibodies. Examination of mutations that persist and accumulate led to identification of antigenically significant mutations that are contained in five...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antibodies, Neutralizing

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Antigens, Viral

Share to Epitopes

Share to Hemagglutinin Glycoproteins, Influenza Virus

Share to Influenza A Virus, H3N2 Subtype

Share to Seasons

Share to Vaccination

Source

Open in PubMed Open full text

Identifiers

PMID: 22848649
DOI: 10.1371/journal.pone.0041895
PMCID: PMC3405050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses.PMID 22848649Read ↗

Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape.Semantic proximity Read ↗

Immunodominance and Antigenic Variation of Influenza Virus Hemagglutinin: Implications for Design of Universal Vaccine ImmunogensSemantic proximity Read ↗

Amino Acids in Hemagglutinin Antigenic Site B Determine Antigenic and Receptor Binding Differences between A(H3N2)v and Ancestral Seasonal H3N2 Influenza Viruses.Semantic proximity Read ↗

Subtype- and antigenic site-specific differences in biophysical influences on evolution of influenza virus hemagglutininSemantic proximity Read ↗

Determination of antigenicity-altering patches on the major surface protein of human influenza A/H3N2 virusesSemantic proximity Read ↗

Epistasis facilitates the long-term antigenic evolution of the influenza B virus hemagglutininSemantic proximity Read ↗

Antigenic and virological properties of an H3N2 variant that continues to dominate the 2021–22 Northern Hemisphere influenza seasonSemantic proximity Read ↗

Neutralizing Epitopes and Residues Mediating the Potential Antigenic Drift of the Hemagglutinin-Esterase Protein of Influenza C Virus.Semantic proximity Read ↗

Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010-2011 influenza season: high prevalence of mutations at antigenic sites.Semantic proximity Read ↗

Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014-2015 Influenza Season.Semantic proximity Read ↗

The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza VirusesSemantic proximity Read ↗

Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United StatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.