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Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010-2011 influenza season: high prevalence of mutations at antigenic sites.

Influenza and other respiratory viruses - 1 Mar 2014

Eshaghi Alireza, Duvvuri Venkata R, Li Aimin, Patel Samir N, Bastien Nathalie, Li Yan, Low Donald E, Gubbay Jonathan B

Abstract excerpt

BACKGROUND: The direct effect of antigenic site mutations in influenza viruses on antigenic drift and vaccine effectiveness is poorly understood. OBJECTIVE: To investigate the genetic and antigenic characteristics of human influenza A (H3N2) viruses circulating in Ontario during the early 2010-2011 winter season. STUDY DESIGN: We sequenced the hemagglutinin (HA) and neuraminidase (NA) genes from 41 A(H3N2)...

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Identifiers

PMID: 24313991
DOI: 10.1111/irv.12219
PMCID: PMC4186474

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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