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Article

The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza Viruses

28 Jan 2019

Abstract excerpt

While influenza A viruses of subtype H2N2 were at the origin of the Asian influenza pandemic, little is known about the antigenic changes that occurred during the twelve years of circulation in humans, the role of preexisting immunity, and the evolutionary rates of the virus. In this study, the antigenic map derived from hemagglutination inhibition (HI) titers of cell-cultured virus isolates and ferret...

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PMID: 30700609
DOI: 10.1128/jvi.01907-18

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