Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014-2015 Influenza Season.

Cell reports - 7 Jul 2015

Chambers Benjamin S, Parkhouse Kaela, Ross Ted M, Alby Kevin, Hensley Scott E

Abstract excerpt

Influenza vaccines must be updated regularly because influenza viruses continuously acquire mutations in antibody binding sites of hemagglutinin (HA). The majority of H3N2 strains circulating in the Northern Hemisphere during the 2014-2015 season are antigenically mismatched to the A/Texas/50/2012 H3N2 vaccine strain. Recent H3N2 strains possess several new HA mutations, and it is unknown which of these mutations...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Antigens, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Binding Sites, Antibody

Share to Disease Outbreaks

Share to Genetic Drift

Share to Hemagglutinins

Share to Influenza A Virus, H3N2 Subtype

Share to Molecular Sequence Data

Source

Open in PubMed Open full text

Identifiers

PMID: 26119736
DOI: 10.1016/j.celrep.2015.06.005
PMCID: PMC4487778

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of Hemagglutinin Residues Responsible for H3N2 Antigenic Drift during the 2014-2015 Influenza Season.PMID 26119736Read ↗

The antigenic architecture of the hemagglutinin of influenza H5N1 viruses.Semantic proximity Read ↗

Antigenic Variation of Clade 2.1 H5N1 Virus Is Determined by a Few Amino Acid Substitutions Immediately Adjacent to the Receptor Binding SiteSemantic proximity Read ↗

Identification of Amino Acid Substitutions Supporting Antigenic Change of Influenza A(H1N1)pdm09 VirusesSemantic proximity Read ↗

The Molecular Basis for Antigenic Drift of Human A/H2N2 Influenza VirusesSemantic proximity Read ↗

Amino acid substitutions in antigenic region B of hemagglutinin play a critical role in the antigenic drift of subclade 2.3.4.4 highly pathogenic H5NX influenza virusesSemantic proximity Read ↗

Discordant antigenic drift of neuraminidase and hemagglutinin in H1N1 and H3N2 influenza viruses.Semantic proximity Read ↗

Emergence of an antigenically drifted and reassorted influenza B virus at the end of the 2024-25 influenza season.Semantic proximity Read ↗

Key Amino Acid Residues That Determine the Antigenic Properties of Highly Pathogenic H5 Influenza Viruses Bearing the Clade 2.3.4.4 Hemagglutinin GeneSemantic proximity Read ↗

Emergence of an Antigenically Drifted and Reassorted Influenza B Virus at the end of the 2024-25 Influenza SeasonSemantic proximity Read ↗

Haemagglutinin mutations and glycosylation changes shaped the 2012/13 influenza A(H3N2) epidemic, Houston, Texas.Semantic proximity Read ↗

Genetic characterization of seasonal influenza A (H3N2) viruses in Ontario during 2010-2011 influenza season: high prevalence of mutations at antigenic sites.Semantic proximity Read ↗

Epitopes in the HA and NA of H5 and H7 avian influenza viruses that are important for antigenic driftSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.