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Article

Concomitant BCR-ABL1 translocation and JAK2(V617F) mutation in three patients with myeloproliferative neoplasms.

Diagnostic molecular pathology : the American journal of surgical pathology, part B - 1 Sept 2012

Hummel Jennifer M, Kletecka M Carmen Frias, Sanks Jennifer K, Chiselite Mihaela D, Roulston Diane, Smith Lauren B, Czuchlewski David R, Elenitoba-Johnson Kojo S J, Lim Megan S

Abstract excerpt

Chronic myeloproliferative neoplasms (MPN) are clonal disorders of hematopoietic stem cells, which fall into distinct categories based on a number of characteristics including the presence of the BCR-ABL1 gene fusion (chronic myelogenous leukemia) or the JAK2(V617F) mutation (polycythemia vera, primary myelofibrosis, and essential thrombocythemia). One of the criteria in the 2008 World Health Organization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22847163
DOI: 10.1097/PDM.0b013e318246975e

Genes

ABL1
BCR
JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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