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Article

Rare Case of Accelerated-Phase Chronic Myeloid Leukemia Diagnosed During Treatment for JAK2 V617F-Positive Primary Myelofibrosis.

Laboratory medicine - 3 Nov 2022

Ryu Jeayeon, Chu Daehyun, Park Bosung, Kim Miyoung, Cho Young-Uk, Hwang Sang-Hyun, Jang Seongsoo, Seo Eul-Ju, Lee Jung-Hee, Park Chan-Jeoung

Abstract excerpt

Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by the expansion of myeloid lineage cells. Chronic myeloid leukemia (CML) is characterized by a BCR-ABL1 fusion gene that causes constitutive tyrosine kinase activity. Polycythemia vera, essential thrombocythemia, and primary myelofibrosis (PMF) are frequently associated with driver mutations in genes such as JAK2,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35243502
DOI: 10.1093/labmed/lmac011

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Rare Case of Accelerated-Phase Chronic Myeloid Leukemia Diagnosed During Treatment for JAK2 V617F-Positive Primary Myelofibrosis.PMID 35243502Read ↗

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