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Article

Sequential Development of JAK2V617F Mutation and BCR-ABL1 Fusion in Individual Patients With Myeloproliferative Neoplasms.

Archives of pathology & laboratory medicine - 1 Jun 2022

Zhao Yue, Reddi Deepti, McCracken Jenna, Iranzad Natasha, Rehder Cathrine, Neff Jadee, Wang Endi

Abstract excerpt

CONTEXT.—: Concomitant BCR-ABL1 and JAK2V617F in myeloproliferative neoplasms (MPNs) is rare, and its pathogenesis and clinical significance are unclear. OBJECTIVE.—: To investigate the clonal relationship between the 2 genomic alterations, as well as the clinicopathologic impact. DESIGN.—: Retrospective analysis of MPNs with sequential development of BCR-ABL1 and JAK2V617F. RESULTS.—: Of 6 cases, 5 had...

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Identifiers

PMID: 34506622
DOI: 10.5858/arpa.2021-0096-OA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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