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Article

First Philippine report of myeloproliferative neoplasms with concurrent JAK2 and BCR::ABL1 mutations.

BMJ case reports - 10 Aug 2026

Amadore Rene A, Yap Rowel David R, Quero-Taggaoa Anne Kristine H

Abstract excerpt

Myeloproliferative neoplasms (MPNs) are broadly classified into BCR::ABL1-positive chronic myeloid leukaemia (CML) and BCR::ABL1-negative subtypes such as polycythaemia vera (PV), essential thrombocythaemia and primary myelofibrosis. Although traditionally considered mutually exclusive, rare cases of coexisting BCR::ABL1 rearrangement and Janus kinase 2 (JAK2) mutation have increasingly been recognised.We report...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42575681
DOI: 10.1136/bcr-2025-271701

Genes

JAK2
ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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